Principal Scientist, Cell Culture Development
- Lead upstream process development for biologics.
- Provide scientific direction and technical expertise in cell culture.
- Collaborate cross-functionally to support patient outcomes.
We’re hiring a Principal Scientist in Cell Culture Development to join our team in Melbourne and play a key role in advancing biologics development.
This is a senior technical role where you’ll lead upstream process development, provide scientific direction, and help bring high-quality recombinant products from early development through to manufacturing readiness. You’ll work across platforms, collaborate cross-functionally, and contribute to impactful programs that support patient outcomes.
Your Responsibilities:
- Provide scientific leadership and technical expertise in cell culture process development, optimisation, and scale-up
- Design and execute upstream development strategies across high-throughput and mid-scale platforms
- Lead and contribute to experimental planning, execution, and datainterpretation with strong scientific rigour
- Support process development across the full lifecycle from clone selection through to process characterisation
- Guide and mentor team members, sharing expertise and building capability
- Contribute to regulatory documentation and submissions
- Collaborate with cross-functional teams to enable tech transfer and manufacturing readiness
Skills & Experience:
- Postgraduate degree (MSc, PhD, MEng or equivalent) in a relevant field
- Significant experience in cell culture process development (industry or advanced academic setting)
- Proven track record working with recombinant protein production or similar systems
- Comfortable working in cross-functional and multicultural teams
Experience with the following is highly regarded:
- Mammalian cell culture, particularly CHO systems
- Early- and late-stage process development
- Media development and metabolic modelling
- Process optimisation aligned to product quality attributes
- Bioreactor scale-up and scale-down
- Technology transfer or implementation of manufacturing processes
Why join us?
- Work on cutting-edge biologics development
- Influence key scientific and technical decisions
- Collaborate with a highly skilled, multidisciplinary team
- Be part of work that ultimately supports patient impact
If you’re a scientist who enjoys combining deep technical expertise with leadership and collaboration, we’d love to hear from you.
Applications Close on September 30, 2026
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